Eye Drops “Betaxolol" (instructions for use and refer them to selective beta-blockers long-acting) is actively used in ophthalmic practice, and the pill is widely used in the treatment of several cardiovascular diseases.
Means “Betaxolol” is produced in the form of tablets and eye drops. One white tablet, film-coated, contains 20 mg of active component hydrochloride betaxolol. As additional ingredients are: carboximetilkrahmal sodium, magnesium stearate, microcrystalline cellulose, lactose monohydrate, Aerosil. The composition of the shell contains: polyvinyl alcohol, white Opadry-2, macrogol, talc, titanium dioxide.
Packed 10 pieces in an aluminium blister packs of tablets “Betaxolol”. Instructions for use enclosed in a cardboard box.
Eye drops for 1 ml accounted 5.6 mg active ingredient hydrochloride betaxolol. The secondary substances in the drugs are: sodium hydroxide, benzene chloride, hydrochloric acid, dihydrate edetate disodium, sodium chloride, water. It is a yellowish transparent substance. The solution is confined in a bottle-an infusion (5 or 10 ml). Issued also a tube-dropper with a dosage of 1.5-5 ml In a cardboard box put instructions and a vial-dropper.
The shelf life of the medications (pills and eye drops) is three years. After opening bottle drops can be stored for more than twenty-eight days.
Pharmacological action of the drug is characterized by beta-adrenoblokiruta selective antianginal, antihypertensive, antiarrhythmic, protivoglaucomnoe orientation.
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Blocks beta1-adrenergic receptors, has no sympathomimetic activity, and allocated small membrane stabilizing properties. Reduces the sensitivity of tissues to catecholamines slows the Central impulses, stopping the secretion of renin. Reduces the degree of heart rate and reduces oxygen consumption by the myocardium (anti-anginal properties). Blocks occurring ectopic foci in the Atria, AV-combinations.
The Result is observed after two hours after administration and the maximum concentration of drug in the body is fixed in 3-4 hours and lasts for 12-24 hours, returning to normal with regular use of the drug within 7-14 days. Protects against increase in blood pressure during physical exertion and psychological stress.
Treatment of high blood pressure is by reducing the mass of the myocardium of the left ventricle and increasing its contractile functions. About 75% of patients with mild or moderate hypertension respond well to such monotherapy. Prolonged use of medications does not affect the regulations of lipid metabolism and the excretion of sodium. In people with asthma and bronchitis in the chronic form, does not reduce respiratory function.
Eye Drops “Betaxolol" (instruction manual says about the effects of the drug on the reduction of intraocular pressure by reducing aqueous fluid) does not cause such side effects like night blindness, miosis, spasm of accommodation and blurring of vision.
The Effect is half an hour after application, the maximum concentration observed after two hours and lasts for twelve hours.
Recommended to take with diagnosis "arterial hypertension", the transitory attack of myocardial ischemia (angina), akathisia provoked by neuroleptics, tablets “Betaxolol”.
Eye drops (instruction manual advises to consult with doctor before use) shows when the disease of open-angle glaucoma, intraocular hypertension. Doctors prescribe the drug after laser trabeculoplasty. Use with long-term antihypertensive therapy, the need for which arose from the ophthalmic surgical intervention.
Despite the proven efficacy of the drug “Betaxolol” (the instructions for use of the medicine advised to strictly observe the prescribed dose and not to self-medicate), its application has certain contraindications. These include hypersensitivity to the active component of the medicament and additional substances in its composition. He also banned if vicarous sinusova aetiology (less than 45-50 u./min) and weakness sinusnogo hub. Not medication to use AV blockade II-III degree arterial hypotension. Contraindicated “Betaxolol” people with cardiogenic shock, patients with severe heart failure and severe obstructive respiratory failure.
Caution should be taken when chronic pneumonia, patients with unstable angina, predisposition to bradycardia. Caution should cause AV blockade I extent of peripheral blood circulation failures. This applies especially to patients with diabetes, hypoglycemia, liver diseases and kidney, hyperthyroidism. Doctors should monitor the medication of patients with muscle weakness in elderly and children.
During pregnancy and lactation the drug is accepted if the expected benefit to the mother outweighs the potential risk to the fetus. At the time of treatment should stop breastfeeding.
Price, reviews, composition – this is the positive side of drugs that make patients again and again to select it.
The Pills must be drink in the morning. Hypertension tablets taken as a single dose, starting dose 10 mg. a week If desired effect is not obtained, the dose may be increased to 20 ml If the expected result again failed to reach, then after 7-14 days, increase the dose to 40 mg.
Patients with impaired renal function treated by dialysis, and the elderly should use the drug in an amount of 5 mg once. If necessary, the dose can be increased every 14 days by 5 mg. recommended not to exceed the maximum dose of 20 ml “Betaxolol” - instructions for use.
Abstract advises to use eye drops for glaucoma. Instillation must be carried out strictly in the conjunctival SAC. The dose is one drop. This event is carried out two times a day. During the first month of treatment, the doctor needs to monitor the intraocular pressure of the patient.
Claims that can lead to side effects the drug “Betaxolol" instructions for use. The price of the medicine affordable, making it accessible to all segments of the population (80 RUB. for a bottle with a volume of 5 ml and 370 RUB for 30 tablets).
In the treatment of ‘Betaxolol” can be a chronic fatigue and headache, dizziness, drowsiness, sleep disturbance, anxiety, depression. Decreased concentration, nightmares, hallucinations, amnesia, neuralgia, vestibular disorders.
Some patients were observed impotence and violation of the process of urination, pain in the breast (in women), prostate, fibrocystic changes. Observed indigestion, diarrhea, dry mouth, nausea, vomiting, constipation, pain in the abdomen. The drug sometimes affects infectious lung disease, dyspnoea, causes chest pain, pharyngitis, rhinitis, sinusitis. Fixed spasms of the bronchi, shortness of breath, respiratory failure.
Among the side effects also identified the following: bradycardia, hypotension, myocardial infarction, heart failure, leukocytosis, thrombocytopenia, purpura and other diseases. Rarely had arthralgia, tendinitis, myalgia.
Can be rash, alopecia, allergic reactions, eczema, weight changes, erythema, hypothermia, exacerbation of psoriasis, hypertrichosis, prurigo.
The Application of drops to the eye can cause watery eyes, dry eyes, blurred vision, photophobia, keratitis, erythema, foreign body sensation in eye, corneal sensitivity, anisocoria and photophobia.
During therapy with the drug Betaxolol (instruction manual describes in detail the dose and method of treatment) are often observed change in performance of laboratory tests. It can be a false positive reaction in anti-doping, the increase in titer of antinuclear antibodies, etc.
Instructions for use (equivalents have the same active substance and have a similar effect) strongly recommends that you follow the dosage. Otherwise, you may encounter such unpleasant symptoms:
In this case, is assigned to conventional treatment as follows:
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Alin Trodden - author of the article, editor
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