Pharmaceutical preparation "Papaverine" (candles). Usage instructions

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2018-03-22 12:50:08

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Pharmaceutical formulation “Papaverine" (candle) instructions for use, clinical and pharmacological group myotropic antispasmodics.

This drug has hypotensive and antispasmodic action. It contributes to a significant reduction of tone and relaxation of smooth muscle in gastrointestinal, respiratory and genitourinary systems, reduces the content of calcium ions.

At admission increased the caseload of the drug observed relaxation of the myocardium and reducing blood flow velocity. The medication does not have much effect on the Central nervous system.

The Drug “Papaverine" (the spark), instruction manual notes, is characterized by rapid absorption. In plasma it binds to proteins. Established that this drug readily crosses the blood brain barrier. Biotransformiroetsa it in the liver. The half-life can range from thirty minutes to two hours.

In each suppository contains 0.02 g of papaverine hydrochloride.

The Drug “Papaverine”. Application

This drug is used to eliminate spasms of smooth muscles in the abdomen – cholecystitis, pilorospazme, spastic colitis, renal colic, and angina pectoris, spasms in the brain. In addition, the drug is used as an adjunct for sedation.

The Drug “Papaverine" (the spark), instruction manual informs you, is contraindicated in case of hypersensitivity of the patient to the drug component, AV blockade, glaucoma, severe renal failure, the elderly and children.

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With extreme caution this tool has been appointed in the States after receiving a traumatic brain injury, as well as kidney failure in the chronic form, hypothyroidism, prostatic hypertrophy, supraventricular tachycardia.

The Drug “Papaverine" (the spark), instructions for use notes especially, can cause certain unwanted effects, among which are the following:

  • Some violations of the cardiovascular system, such as AV block, lowering blood pressure, ventricular arrythmia;
  • Failures in the functioning of the digestive tract-diarrhea, constipation, activation of hepatic transaminases;
  • Additionally, you may develop itching, allergic reactions, eosinophilia.

In combination with barbiturates enhanced the spasmolytic effect of the considered drug. Its hypotensive effect is increased when combined with antidepressants (tricyclic), reserpine, quinidine and procainamide.

Symptoms of overdose are: double vision and other visual disturbances, drowsiness, weakness, low blood pressure. Necessary treatment – immediate gastric lavage and maintenance of blood pressure.

Adult patients indicated one or two suppositories (twenty to forty milligrams) a maximum of three times per day. This form of drug is most optimal in situations where the use of oral means difficult (diarrhea or vomiting). In addition, suppositories shown to persons suffering from impaired functioning of the gastrointestinal tract.

The Drug “Papaverine,” the tone of the uterus in pregnant women helps to improve blood flow to the muscles of the body, and this has a positive effect on the fetus, reduces the risk of miscarriage.

The efficiency of the medication is reduced in the case if the patient smokes. For the period of treatment should completely refrain from drinking alcohol.


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Alin Trodden - author of the article, editor
"Hi, I'm Alin Trodden. I write texts, read books, and look for impressions. And I'm not bad at telling you about it. I am always happy to participate in interesting projects."

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