"Aspirin": instruction manual, reviews, analogs

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2019-03-26 05:20:39

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To prevent the development of such dangerous disease, as myocardial infarction in medical practice to use the drugs based on acetylsalicylic acid. Antiplatelet and anti-inflammatory action has the means “Aspirin”. Instruction manual describes in detail the therapeutic effect, indication and rules of taking the medicine. Before starting treatment, you should be familiar with the indications and contraindications concerning the application and be sure to consult with your doctor.

“Aspirin": composition

The Main active component of tablets “Aspirin” is acetylsalicylic acid, which is used as the primary prevention of strokes and heart attacks.

Aspirin composition

One tablet contains 75 mg of active substance. Excipients: silica colloidal anhydrous, cellulose microcrystalline, stearic acid.

How does?

Acetylsalicylic acid is a nonsteroidal anti-inflammatory substances that have antipyretic, analgesic and antiplatelet effect. The main component has an inherent ability to thin the blood, decrease blood coagulation by inhibiting the synthesis of thromboxane A2 in the aggregation of platelets. It has a vasodilatory effect (minor). The drug ‘Aspirin” reduces the risk of myocardial infarction, stroke in the brain.

Aspirin usage instructions

In the digestive tract the drug is absorbed almost completely. The basic process occurs in the small intestine. Thanks to the protective shell is able to minimize the negative effect of acetylsalicylic acid on gastric mucosa. Biotransformiroetsa the active ingredient in the liver. In the body of matter quickly bind with the protein in the blood and distributed throughout the system. The main route of excretion – the kidney.

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Indications for use

The Drug most often prescribed to patients for the prevention of myocardial infarction (primary and secondary) angina. Also the indications include the following cases:

  • Prevention of thrombosis.
  • Prevention of clogging of blood vessels by emboli-particles, which normally should not be in the serum.
  • Prevention of stroke brain ischemic type.
  • Mitral valve Prolapse.
  • Transient ischemic attack (reducing the risk).
  • Prevention of blood clots in the deep veins.
  • Prevention of heart attack in individuals who are at risk.

Causes of stroke and heart attack

Stroke is a disease in which the blood circulation in the vessels of the brain, that is, there ceases to receive oxygen and nutrients necessary for its normal functioning. The situation is similar with a heart attack, which most often affects the heart muscle (myocardium). The main reasons for the development of these pathologies – thrombosis and atherosclerosis. In the case of stroke, the brain may be bleeding, what distinguishes the illness from a heart attack.

Aspirin price

The main factors predisposing to the development of cardiovascular disorders include:

  • Hypertension (high blood pressure).
  • Diabetes.
  • Problems with excess weight.
  • Atherosclerosis.
  • Improper diet.
  • Regular consumption of alcohol, Smoking.
  • Genetic predisposition.

“Aspirin” instruction manual recommends that to prevent the clogging of blood vessels by blood clots, thin the blood. Based tablets of acetylsalicylic acid are considered to be quite effective.

Method of application

The Tablets covered with a special membrane that helps to “deliver” the active substance to the destination, that is, in the intestine, thereby reducing the deleterious effect on the stomach. Therefore, when medication is to chew it is prohibited. The dosage will depend on the patient's diagnosis.

A Patient with suspected acute myocardial infarction should take the drug “Aspirin” at a dose of 75 to 300 mg per day to prevent a lethal outcome. The recommended course of treatment-1 month. As a secondary prevention of heart attack and stroke take pills for the specialist appointment. Daily dose of tools “Aspirin” – 75-300 mg.

For the prevention of blood clots after surgery on vessels administered 75-150 mg “Aspirin” per day, or 300 mg a day. The same amount of active ingredient be required of patients at risk.

Features of the drug “Aspirin”

Acetylsalicylic acid should not be prescribed to patients under the age of 16 years. This can lead to undesirable consequences, e.g., Reye's syndrome. A pathological condition occurs in many children and adolescents who take the drugs based on acetylsalicylic acid. The disease affects the functionality of the kidney, causing brain swelling and inflammation in the liver. To determine the syndrome is possible by prolonged vomiting that occurs after taking the drug. This condition is extremely dangerous for human body and requires immediate medical help.

Prescribing in pregnancy

Means ‘Aspirin” in pregnancy can be prescribed only by the attending physician in case of emergency. During clinical studies it was found that suppression of prostaglandin synthesis has no negative impact on fetal development and pregnancy in General. At the same time acetylsalicylic acid can be administered in the first trimester, when laid the basic system of the fetus.

Aspirin during pregnancy

In the last trimester of pregnancy inhibitors of prostaglandin synthesis can cause cardio-pulmonary toxicity and to affect the health of the kidneys. Acetylsalicylic acid is not indicated in the last stages of gestation to prevent prolonged bleeding caused by antiplatelet action. There is also a risk of deterioration of the contractile activity of the uterus that extends the process of delivery.

In need of treatment the drug is prescribed in minimum dose and short-course therapy.

Special instructions regarding application of medication

Caution should be take “Aspirin 75” those with hypersensitivity to anti-inflammatory and analgesic substances. Acetylsalicylic acid may affect the functionality of the kidneys in the case history of the patient has ailments such as renal failure, a pathological condition of the vessels.

Aspirin analogues

Patients with a predisposition to allergic reactions should be careful to take the pill. The current component can cause bronchospasm, urticaria, itching of the skin.

Even small doses of the drug can affect the rate of excretion of uric acid, which is dangerous for patients with this diagnosis, as gout. The inhibitory effect of the basic substance regarding platelet aggregation persists for several days. Therefore, medication is recommended to stop before planned surgery (including before tooth extraction) at least 5 days to prevent the development of bleeding.

The presence of peptic ulcer disease based tablets of acetylsalicylic acid can be assigned only to the attending physician.

Contraindications

The Drug “Aspirin” instruction on the application prohibits the use, if the patient has intolerance or hypersensitivity to the components in the composition. Tablets cannot be used for the treatment of patients with thrombocytopenia, hemorrhagic diathesis, hemophilia. Contraindication is also ulcerative pathology of the gastrointestinal tract in the acute stage, renal and hepatic insufficiency, age 16, asthma.

Interaction with other drugs

At the same time Forbidden to take acetylsalicylic acid (tablets “Aspirin”) and methotrexate, if weekly last dose exceeds 15 mg. Should be avoided concurrent use of “Aspirin” and anticoagulants, thrombolytics. This significantly increases the risk of bleeding.

Aspirin 75

It is Undesirable to apply high doses of the drug with non-steroidal anti-inflammatory drugs to prevent the development of ulcerative disease of the digestive system and bleeding of the gastrointestinal tract.

The Simultaneous use of drugs with digoxin enhances the concentration of the latter in blood serum. Hypoglycemic effect of the drugs from the group of sulfonylureas used for the treatment of diabetes, intensified.

Not recommended to take valproic acid with the drug “Aspirin”, to avoid increased toxic effects on the body acetylsalicylic acid.

Interaction with alcohol

The Drug “Aspirin” the instruction forbids to combine with alcohol. Components work synergistically with each other, which is a double blow to the mucosa of the digestive tract. In the presence of ulcerative lesions is possible by the development of haemorrhage that is a serious danger to the life of the patient.

The Drugs based on aspirin can be taken not earlier than 12 hours after the adoption of alcoholic beverages. Otherwise, the possible negative consequences for the body.

Overdose Symptoms medication

Overdose drug most often found in the elderly. The main features of the pathological state are:

  • Vertigo.
  • Nausea and vomiting.
  • Confusion.
  • Ringing in the ears.
  • Acute intoxication.
  • Hemorrhage.
  • Respiratory failure.
  • Hearing loss.
  • Hypoglycemia.

Develops the toxic effects of the main substance as a result of long-term therapy or exceeding the recommended daily dosage. Moderate intoxication observed on the background of repeated administration of high doses of the drug. If the plasma concentration of salicylates exceeds 300 micrograms/ml, there is a possibility of acute intoxication, manifested in changes in acid-base balance.

A Patient with symptoms of overdose should be transferred to a medical facility, where he will producecleansing the body and restoring acid-alkaline and electrolyte balance.

Side effects

The Greatest number of negative consequences of taking the pills observed on the part of the gastrointestinal tract. Perhaps the appearance of pain in the epigastric region, diarrhea, nausea, erosions and ulcerative lesions in the mucosa.

From the vascular system the risk of possible bleeding of the nasal passages, gums, digestive tract. The most vulnerable patients with risk of bleeding in the brain in hypertension. Some patients note headache, tinnitus and disorders of spatial orientation after taking the medication “Aspirin”.

Instruction manual warns about possible negative reactions from the immune system. In case of hypersensitivity to the components may occur skin reactions such as urticaria, redness, itching.

“Aspirin”: price and reviews

The Majority of patients taking the drug, satisfied with the result and mild therapeutic effect. Unlike analogue, its dose is somewhat smaller, which reduces the risk of side effects, e.g., tinnitus, dizziness. It is also worth noting the relative safety of the drug “Aspirin”. Patient testimonials confirm that, thanks to the protective shell, virtually no negative effect on the organs and mucous surface of the digestive system. To dissolve the drug begins only in the intestine.

Drug Aspirin

“Aspirin”, the price of which ranges from 90 to 170 rubles for 30 tablets, are more accessible other drugs antithrombotic group. The drug has been proven in the prevention of blood clots, stroke, brain and myocardial infarction. Applying “Aspirin” for the appointment of a specialist and adhering to individual treatment recommendations, it is possible to avoid the negative consequences and side effects.

What to replace?

The Pharmaceutical market offers a huge choice of drugs are similar actions. Medicinal drug “Aspirin” counterparts has the following:

  • “Aspirin Cardio” – the most popular means to thin the blood, prevent the formation of clots in blood vessels. Can be used for a long period of time.
  • “Aspecard” – drug anti-inflammatory, analgesic and antipyretic actions. Used as antithrombotic drugs.
  • “Drug” – synthetic antiplatelet drug used to prevent cardiovascular pathologies. The main active ingredient-clopidogrel bisulfate.


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Alin Trodden - author of the article, editor
"Hi, I'm Alin Trodden. I write texts, read books, and look for impressions. And I'm not bad at telling you about it. I am always happy to participate in interesting projects."

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