What "Ibuprofen" of the prescribed to patients? We will tell you in this article. You learn from it about how is referred to tool like and in what dosage it should be taken and so on.
In what form is issued "Ibuprofen"? Instruction manual, specialists have reported that this drug produced in various forms.
Why “Ibuprofen" is used in medical practice? According to the instructions, this medication is a nonsteroidal anti-inflammatory agent. He is able to exert anti-inflammatory, antipyretic and analgesic effects. Experts say that this tool indiscriminately blocks ЦОГ2 and ЦОГ1.
The Principle of action of ibuprofen is to slow the synthesis of prostaglandins, that is, mediators of inflammation, pain, and hyperthermic reactions.
What are the pharmacokinetic rates have the tablet "Ibuprofen"? The use of oral forms of the drug provides a high and rapid absorption from the gastrointestinal tract.
The Largest concentration of ibuprofen in plasma observed after 120 to 240 minutes after his admission. Connection with plasma proteins is more than 90 % and the elimination half-life – 2 hours.
The Drug "Ibuprofen" (suspension and tablets) is slowly released into the joints. Its active ingredient is delayed in the synovial tissue. This provides a large concentration of the current component.
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After intake about 60% of the inactive R-form medications transformirovalsya in the active S-form.
This medication is metabolized. It is excreted via kidneys (unchanged) and with bile.
Why “Ibuprofen" may be assigned to patients? According to the instructions, this drug has the following indications for use:
What other purposes can be used "Ibuprofen"? What are these tablets prescribed to patients? Doctors say that this drug is actively used for symptomatic therapy. It is well and quickly reduces inflammation and pain (only at the time of use), but the progression of the disease has no effect.
Why “Ibuprofen" using the patients we described above. As for contraindications, these include the following patient:
What are the contraindications of the drug "Ibuprofen"? Syrup for children it is not recommended to give babies under 3 months, and other forms of medications – up to 6 years. Also this medication should not be used during pregnancy.
Under any conditions, you must be careful to prescribe medication "Ibuprofen"? The use of (reviews about this tool will be presented below) of this drug in the elderly, and people with heart failure, arterial hypertension and coronary heart disease must be strictly monitored by a doctor.
Also with caution this medication is prescribed for cerebrovascular diseases, dyslipidemia, diabetes, diseases of the arteries (peripheral), Smoking, enteritis, regular alcohol consumption, cirrhosis of liver, gastritis, nephrotic syndrome, hyperbilirubinemia, colitis, blood diseases of unknown origin and while breastfeeding.
Methods of using this drug depends on its forms of production.
At what dose is shown "Ibuprofen" for children? Instructions for use States that, in relation to the tablets, syrup acts much faster. Before using this form, shake well. The dosage of this medication must only find a pediatrician, depending on the patient's condition.
Suppositories "Ibuprofen" designed specifically for infants. They are used rectally and take effect after 30 minutes. When feverish or pain syndrome a single dose of this drug is 5-10 mg per 1 kg of weight of the child. To use candles preferably with an interval of 6-8 hours.
How should I use the ointment "Ibuprofen"? Gel, a strip of 1.5 cm, is applied to the lesion with light massage movements. Charismatic should avoid getting the drug on mucous membranes and open wounds. Otherwise, the medication is required immediately wash off with warm water.
Not harmful pills "Ibuprofen" for children? Instruction manual States that this form of drug is not desirable to give to kids under 6 years.
Take this medication should be in between meals. Usually it is administered in an amount of 5-10 mg per 1 kg of body weight three times a day. This daily dose should not be more than 20 mg per kg.
In rheumatoid arthritis and other diseases of the joints, the drug is administered in the amount of 40 mg/kg (but not more).
When taking high doses of the drug, the patient may develop the following symptoms: nausea, lethargy, abdominal pain, drowsiness, vomiting, tinnitus, depression, metabolic acidosis, headache, acute renal failure, coma, bradycardia, decreased blood pressure, atrial fibrillation, respiratory failure and tachycardia.
Treatment – urgent gastric lavage (within 60 min after the overdose), administration of activated charcoal, alkaline water, and forced diuresis.
Does the emergence of adverse drug reaction "Ibuprofen"? Gel for external use never causes undesirable consequences. With regard to oral forms of the drug, they can cause the following effects:
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Alin Trodden - author of the article, editor
"Hi, I'm Alin Trodden. I write texts, read books, and look for impressions. And I'm not bad at telling you about it. I am always happy to participate in interesting projects."
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