Hyperandrogenism in women: causes, symptoms, treatment. What is the danger of hyperandrogenism in women

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2018-04-02 19:14:18

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In medicine is known for this problem of hyperandrogenism in women. Causes, symptoms, treatment with this diagnosis require assessment and participation of qualified doctors. Although this disease is extremely difficult to overcome completely, to turn to doctors better without delay.

Diseases

When it comes to this disease, such as hyperandrogenism in women, causes, symptoms, treatment and preventive measures are always associated with this problem, as the impact of androgenov on the body. This process leads to the appearance in the female appearance of masculine traits and other not very pleasant changes. In more detail, we are talking about such problems as the appearance of vegetation on the face and body, deep voice, and also changes some elements of the shape.

hyperandrogenism in women symptoms causes treatment

It is Worth noting the fact that the pathology of the female endocrine system occur frequently, and are not only able to lead to unpleasant external changes, but also cause infertility. Therefore, the appearance of the first symptoms of hyperandrogenism, should immediately plan a visit to the doctor.

Why pathology develops

The Theme of “hyperandrogenism in women: causes, symptoms and treatment” Is very important for the fairer sex, since the problem appears about 20% of patients. So it makes sense to pay attention to those factors and processes that lead to the development of this disease.

The main reason to determine the AGS - congenital adrenal hyperplasia. The point is that the adrenals are able to produce many other hormones, in addition to droganov, for example, glucocorticoids. Last appear under the influence of a specific enzyme. The basis for their occurrence are accumulated androgens. Sometimes women at birth there is a defect in the enzyme, causing male hormones are not converted, and is accumulated on an ongoing basis, causing unpleasant changes in the female body.

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There is another process, which is developing hyperandrogenism adrenal Genesis. We are talking about tumors of the adrenal glands. They can be formed also on the background of increasing concentrations of androgens.

The Risk of development of the above pathology appears in the case when there is production of male hormones in the ovaries of women. Moreover, the cells that produce adrogen, can cause the formation of tumors in the ovary region.

The Syndrome of hyperandrogenism is sometimes a consequence of abnormalities of other endocrine organs such as pituitary gland.

Signs of excess androgens

If we talk about the clinical symptoms of elevated concentrations of the male hormone, they can be described as follows:

  • Acne;
  • Hair loss and receding hairline in the forehead (androgena alopecia);

adrenal hyperandrogenism

  • Sebaceous glands start to produce excessive amount of secretion, thus the oiliness of the skin increases;
  • Baritone, which means a lowering of the timbre of the voice;
  • On the belly and chest hairs.

It is Worth noting the fact that the hirsutism - the excessive growth of terminal hairs on the female body, is diagnosed in 80% of patients with this problem, as the syndrome of hyperandrogenism.

With such a disease, some women may menstrual cycle, the complete absence of menstruation, as well as cardiac hypertrophy, obesity, infertility and hypertension.

The Concentration of male hormones may lead to greater susceptibility of the female body to infections of various types. It is also possible fatigue and tendency to depression.

Acne and sebaceous gland

To have a clear understanding of what to do with the problem of hyperandrogenism in women causes, symptoms, treatment and diagnosis should be considered thoroughly. Because the factors that contribute to the development of the disease have been reviewed above, it makes sense to study the peculiarities of the symptomatology.

If you touch such problems as acne, it is worth noting that they are the result of keratinization of the follicle wall and increased sebum production, which stimulates the concentration of androgens, including in the plasma. With such symptoms, as a rule, appoint KOK or antiandrogens, which allows to significantly improve the patient's condition.

hyperandrogenism adrenal Genesis

Also under the influence of male hormones in androgenzawisimah areas appear pigmented, thick, coarse hair instead of vellus. This usually occurs in puberty. The effect of androgen on the eyebrows, eyelashes, temporal and occipital parts is minimal.

Adrenal hyperandrogenism

It is Worth Recalling that the adrenal glands are two endocrine glands that are located directly above by the kidney.

They are the source of 95% of produced androgen (DHEAS sulphate). The complexity of the hyperandrogenism associated with these glands, boils down to the fact that the pathology has an innate character and makes itself felt amid androgenital syndrome. It leads to a critical reduction in the female body level of enzymes necessary for the production of hormones such as glucocorticoids.

Hyperandrogenism adrenal Genesisoslablen It is this deficit which leads to an increase in the concentration of other hormones - pregnenolone, progesterone, etc. These changes culminate in increased production of androgen in the female body.

hyperandrogenism

Sometimes diagnosed pathology, which was caused by adrenal tumors that produce male hormone. According to statistics, this form of the disease as adrenal hyperandrogenism is fixed in 30-50% of women who have problems with androgen.

Effect on ovaries

High concentration of male hormones can also affect the functioning of the ovaries. In most cases, this problem makes itself felt through two forms: hiperseks and polycystic. It is important to pay attention to the fact that the risk of developing this disease in women increases with regular practice of power sports.

Ovarian hyperandrogenism is a result of the slowdown in the growth of follicles under the influence of androgens. Because of them and consist of the ovaries, the outcome of these processes is the fusion of the latter. The medical name for this problem of follicular atresia.

But that's not all the difficulties that accompany the hyperandrogenism of ovarian origin. The point is that male hormone plays the role of a factor, against which develops a pathological formation of fibrous connective tissue, which leads to polycystic. In this situation, the good news is the fact that this problem is faced only 5% of women.

ovarian hyperandrogenism

It is Also worth noting that this form of hyperandrogenism in females is the cause of the failure of the Central regulation of androgen level. This process occurs at the level of the hypothalamus and pituitary. In the end, hormonal balance changes significantly.

Signs you should pay attention

There are a number of symptoms, evidence of the occurrence of the problems described above. That is the place to be this pathology as hyperandrogenism of ovarian origin, can be recognized by the following manifestations:

  • Osteoporosis;
  • Seborrhea;
  • On the face in addition to acne, there is peeling and inflammation, which are difficult to neutralize the usual cosmetic methods;
  • Atrophy of the muscles;
  • Weight;
  • Change the proportions of the female body - masculinization;
  • Roughness of the voice (baritone);
  • Hair growth all over the body even on the face;
  • The formation of bald patches on the head.

In Addition, there are many secondary symptoms, such as increasing the level of glucose in the blood, hypertension, lowered immunity, etc.

Weight

Obesity in women can cause the above-described ovarian hyperandrogenism. With this form of disease often recorded the increase of estradiol level.

A Medical study was conducted, according to which confirmed the following information: as high levels of the male hormone, and forming under the influence of estrogen, have a direct impact on the development of obesity, the corresponding male type.

 hyperandrogenism

These processes are the result of increased insulinozawisimom and subsequent growth of the concentration of male hormones in the body of women suffering from the above described pathology. In some cases androgens have an impact not weight women through the Central nervous system.

Mixed form

Doctors periodically have to deal with the manifestation of several forms of hyperandrogenism. Due to this situation the fact that at the same time there is a violation of the functions of the adrenal glands and the ovaries.

The Possibility of such complications it is important to consider when studying what threat hyperandrogenism in women. In fact, the following occurs: adrenal androgens, concentrating in the adrenal glands, thus increasing the levels of a male hormone in the ovaries. This process occurs in the blood, which leads to increased production of luteinizing hormone. The latter, in turn, provokes the appearance hyperandrogenic syndrome.

The Emergence of mixed forms of pathology may be due to severe injuries, intoxication of the brain or pituitary tumors.

Diagnostics

Initially, the physician should separate the hyperandrogenism from other diseases, against which it develops (acromegaly, Cushing's syndrome, liver disease, etc.). The next step is the definition of hormonal level. This procedure should be performed on an empty stomach in the morning. A similar analysis must be performed three times because of a hormonal background at high concentrations of androgen is constantly changing.

hyperandrogenism of ovarian origin

Attention is drawn to the level of dehydroepiandrosterone, high content of which will be evidence of adrenal hyperandrogenism. Is also important level of ketosteroids in the urine. If its content is outside of the norm, it makes sense to suspect the development of pathology.

Treatment Methods

Hyperandrogenism - this is too serious a problem to ignore the assistance of qualified physicians. And if you analyze the entire course of treatment, we can conclude that he aims to achieve 4 key objectives:

  • Eliminate manifestations on the skin;
  • Normalization of menstrualcycle;
  • Treatment of infertility, which was caused by anovulation;
  • Elimination and prevention of metabolic disorders that are related to the primary disease.

The Diet of hyperandrogenism in women appointed in the event of a significant increase in weight. In this case, it is important to accurately adhere to all doctor's recommendations, only under this condition it is possible to obtain the desired result.

Those patients who intend to have children, in most cases, prescribed hormonal therapy, is able to provide a full ovulation.

diet for hyperandrogenism in women

Women who are not planning a pregnancy, undergoing treatment, including oral contraceptives, and in some cases a wedge-shaped excision of the ovaries.

Drugs for the treatment of hyperandrogenism in women also actively used if the body is unable to neutralize high level of androgen alone. We are talking about such tools as “Metipred”, “Dexamethasone” etc. surgical intervention may be appointed in the case, if the pathology provoked by the tumor.

Results

The High concentration of male hormone in the female body is more than a serious problem, which often develops on the background is no less dangerous diseases. Therefore, the appearance of first symptoms to diagnosis and treatment should be mandatory.


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DE: https://www.tostpost.com/de/gesundheit/322-hyperandrogenaemie-bei-frauen-ursachen-symptome-behandlung-was-ist-gef.html

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Alin Trodden - author of the article, editor
"Hi, I'm Alin Trodden. I write texts, read books, and look for impressions. And I'm not bad at telling you about it. I am always happy to participate in interesting projects."

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